We present an unbiased magnetic resonance imaging template brain volume for pediatric data from birth to 4.5y age range. These volumes were created using 317 scans from 108 children enrolled in the NIH-funded MRI study of normal brain development (Almli et al., 2007, Evans and Group 2006).
Tools for using these atlases can be found in the Software section.
The following publications should be referenced when using this atlas:
VS Fonov, AC Evans, RC McKinstry, CR Almli and DL Collins Unbiased nonlinear average age-appropriate brain templates from birth to adulthood NeuroImage, Volume 47, Supplement 1, July 2009, Page S102 Organization for Human Brain Mapping 2009 Annual Meeting, DOI: 10.1016/S1053-8119(09)70884-5
Copyright (C) 1993–2004 Vladimir S. Fonov, Louis Collins, McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University. Permission to use, copy, modify, and distribute this software and its documentation for any purpose and without fee is hereby granted, provided that the above copyright notice appear in all copies. The authors and McGill University make no representations about the suitability of this software for any purpose. It is provided “as is” without express or implied warranty. The authors are not responsible for any data loss, equipment damage, property loss, or injury to subjects or patients resulting from the use or misuse of this software package.
To view the atlases online, click on the appropriate JIV2 link in the Download section below.
When viewing, the stereotaxic coordinates (X,Y,Z) are displayed in the first row below the volumes. One can use the left most mouse button to click on any image, and the other cross-sectional images will be updated with the appropriate position. You can also hold the middle/rocker mouse button down while moving up or down, to pan through the image plane. Holding ‘Shift’ with the left or middle button will enable dragging and zooming. When looking at the images, remember that left is left and right is right!
You can download templates constructed for different age ranges. For each age range you will get an average T1w, T2w, PDw maps normalized between 0 and 100. Also each age range includes a binary brain mask. NOTE that these templates are smaller then standard MNI-152 template, so if you use them to perform registration in stereotaxic space it will be different coordinate system. It is possible to transform results to MNI-152 space by applying following scaling: 1.21988 in x direction, 1.23510 in y direction and 1.28654 in z direction. Also, you can apply transformation defined in nihpd_asym_44–60_tal.xfm file.